Muhammad Sadeqi Nezhad is a cancer researcher at Clinical and Translational Science Institute (CTSI), University of Rochester Medical Center, New York, USA. Currently, he is working with a great team on development of cancer therapeutics for pancreatic cancer patients with primary and metastatic tumors at Wilmot Cancer Institute. One of his research desires is […]
Cellular Plasticity: Cellular plasticity is characterized by the ability of cells to convert between different (intermediate) cellular states by inducing epithelial-to-mesenchymal transition (EMT), as well as mesenchymal-to-epithelial transition (MET). KAHF Biotech is on a mission to understand the molecular mechanism of cancer cellular Plasticity and characteristic of Mesenchymal cancer cells to develop a Model and therapeutic approaches […]
Muhammad Sadeqi Nezhad has been a peer-reviewer for the following journals Peer-Reviewer Cancer Informatics (IF:2.40). 2022 Computers in Biology and Medicine (IF: 589) (2 Times). January 2022- Mar 2022 Expert Reviews in Molecular Medicine (IF: 233), (2 Times). December 2021- Mar 2022 Frontiers in Immunology (IF: 561), (4 Times). September 2021-April 2022 Springer Nature, Stem […]
Muhammad Sadeqi Nezhad was a Junior Advisor and Research Topic Coordinator and Developer of the research topic entitled “Adoptive T-Cell Therapy, iPSCs Technology, and the CRISPR/Cas9 Genome Editing System: A New Frontier in Cancer Treatment” at Frontiers in Oncology (IF: 5.738). August 2021-September 2022. https://www.frontiersin.org/research-topics/25118/ Topic Editors: Pro. Dung-Fang Lee (MD Anderson Cancer Center, USA), Pro. Jianxun J. Song (Texas A&M University Health […]
Peer-reviewed Publications Review papers Muhammad Sadeqi Nezhad*. “Poly (beta‐amino ester) as an in vivo nanocarrier for therapeutic nucleic acids”. Biotechnology and Bioengineering, (2022). https://doi.org/10.1002/bit.28269. IF: 4.395 Muhammad Sadeqi Nezhad*, Maribel Yazdanifar, Meghdad Abdollahpour-Alitappeh, Arash Sattari, Alexander Seifalian, Nader Bagheri*. “Strengthening the CAR-T cell Therapeutic Application Using CRISPR/Cas9 Technology”. Biotechnology and Bioengineering, (2021). https://doi.org/10.1002/bit.27882. IF: 4.395 […]
Therapeutic nucleic acids are an emerging class of therapy for treating various diseases through immunomodulation, protein replacement, gene editing, and genetic engineering. However, they need a vector to effectively and safely reach the target cells. Most gene and cell therapies rely on ex vivo gene delivery, which is laborious, time-consuming, and costly; therefore, devising a […]
Muhammad Sadeqi Nezhad is a cancer researcher at University of Rochester Medical Center, New York, USA. One of his research desires is to genetically manipulate the cells of interest within the body using in vivo gene delivery approaches instead of ex vivo methods.We will bring a day that there is no need to treat malignant […]